What Are Polynucleotides?

Polynucleotides represent a groundbreaking advancement in aesthetic treatments, marking a significant shift in how we approach skin rejuvenation and anti-ageing therapies. At their core, polynucleotides are complex chains of nucleotides, the fundamental building blocks of DNA and RNA. This intricate molecular structure is pivotal in various biological processes, including cellular repair and regeneration. In the context of aesthetic medicine, polynucleotides harness these natural regenerative properties to offer a novel solution for skin revitalisation. Their emergence in the beauty industry is a testament to the evolving intersection of science and aesthetics, where innovative treatments are increasingly grounded in robust scientific principles.

Anti-Wrinkle Ireland

The role of polynucleotides in aesthetic treatments is multifaceted and profoundly impactful. By stimulating the natural production of collagen and elastin, two vital proteins for maintaining skin elasticity and firmness, polynucleotide treatments effectively combat the visible signs of ageing. As we age, the natural production of these proteins diminishes, leading to the development of wrinkles, fine lines, and a loss of skin firmness. Polynucleotide treatments address these concerns at a cellular level, promoting skin health from within. This approach not only yields visible improvements in skin texture and tone but also aligns seamlessly with the body’s natural processes, ensuring results that are both effective and harmonious with the intrinsic properties of the skin.

Plinest Eye Polynucleotides Treatment

How Do Polynucleotides Work?

Polynucleotides function through a sophisticated biological process, making them a key component in modern aesthetic treatments. These molecules, essential to DNA and RNA, have a unique role in skin rejuvenation and anti-ageing therapies. Their mechanism of action is multi-layered, involving several critical steps:

  • Collagen and Elastin Stimulation:
    Polynucleotides trigger the body’s natural production of collagen and elastin. Collagen provides structural support and firmness to the skin, while elastin contributes to its elasticity. The decline in these proteins due to ageing leads to wrinkles and skin laxity. Polynucleotides help reverse this by boosting the production of these essential proteins.
  • Improvement in Skin Hydration and Texture:
    They enhance the skin’s hydration levels and texture. This is achieved by improving the skin’s capacity to retain moisture, leading to a more hydrated and plump appearance.
  • Cellular Regeneration Promotion:
    Polynucleotides are effective in encouraging the repair and renewal of skin cells. This is particularly beneficial for skin damaged by environmental factors, helping to mitigate the effects of ageing accelerated by external stressors.
  • Integration with Natural Skin Processes:
    The treatment aligns with the body’s natural skin processes. This ensures that the enhancements are effective and maintain a natural appearance.

By stimulating collagen and elastin, polynucleotides not only improve the skin’s firmness and elasticity but also its ability to stay hydrated and smooth. This comprehensive approach to skin rejuvenation addresses various signs of ageing, making polynucleotide treatments a reliable option for those seeking effective skin care solutions. The treatment’s compatibility with the body’s own mechanisms ensures that the results are both impactful and harmonious with the natural properties of the skin, offering a rejuvenated appearance that feels as natural as it looks.

What Can Polynucleotides Be Used For?

Polynucleotide treatments cater to a diverse range of skin issues and conditions, leveraging their unique biological properties for effective results:

  • Reducing Ageing Signs:
    These treatments directly target common ageing signs like wrinkles, fine lines, and skin sagging.They stimulate collagen and elastin production, essential for maintaining skin firmness and elasticity.
  • Enhancing Skin Hydration and Texture:
    Polynucleotides significantly boost skin hydration and improve overall texture.They enhance the skin’s moisture retention capabilities, resulting in a plumper and smoother appearance.
  • Promoting Skin Rejuvenation and Regeneration:
    The treatments excel in rejuvenating and regenerating skin cells. They are particularly beneficial for skin that has suffered environmental damage, aiding in repair and renewal.
  • Addressing Scarring and Hyperpigmentation:
    Polynucleotides effectively reduce the appearance of scars, including those from acne, and help even out skin tone. They work on reducing hyperpigmentation, leading to a more uniform skin complexion.
  • Improving Skin Elasticity:
    The treatments contribute to enhanced skin elasticity. This benefit is especially noticeable in areas prone to elasticity loss, such as the under-eye region and neck.
  • Treating Sun-Damaged Skin:
    Polynucleotides are adept at treating sun-damaged skin, mitigating some effects of UV exposure. They improve skin texture and reduce the visibility of sunspots.
  • Revitalising Overall Skin Health:
    Beyond targeting specific issues, polynucleotide treatments offer holistic skin revitalisation.They improve the overall health and vitality of the skin, contributing to a rejuvenated appearance.

Cost is €350 per session.

Procedure Time

45 minutes


Topical anaesthetic can be applied


Fine lines, wrinkles, skin hydration, and texture

Risks & Complications

Mild swelling / redness, rare allergic reactions




Improved skin texture and elasticity over weeks to months

Treatment needed

2-4 sessions for optimal results

Not Suitable For

Pregnant, breast-feeding individuals, or those receiving IVF treatment


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